Bulg. J. Phys. vol.43 no.4 (2016), pp. 311-319



Effect of Nanofiltration on the Antioxidant Properties of Crataegus monogyna Curative Extracts

D. Mitev1, E. Vlakhov1, T. Vlakhov1, D. Peshev2, N. Hristova-Avakumova3, V. Hadjimitova3
1Georgi Nadjakov Institute of Solid State Physics, Bulgarian Academy of Sciences, 72 Tzarigradsko Chaussee Blvd., 1784 Sofia, Bulgaria
2University of Chemical Technology and Metallurgy, Department of Chemical Engineering, 8 Kl. Ohridsky Blvd., 1756 Sofia, Bulgaria
3Medical University, Department of Medical Physics and Biophysics, 2 Zdrave Str., 1431 Sofia, Bulgaria
Abstract. Treatment of pathological conditions with medicinal and aromatic plants is an ancient approach of treatment and prevention. Basis of a properly conducted therapy is the effective component and precise dosage. To realize the therapeutic properties, in many cases separation and concentration of the active ingredients are essential steps. We chose Crataegus monogyna ("hawthorn") as one of the most common species used in traditional herbalism, which is of considerable interest as a natural sedative and for treating cardiac ailments. The plant parts used medicinally are usually sprigs with both leaves and flowers, or alternatively the fruit. Both of them showed substantial content of antioxidant phytochemicals, although quantification of total phenolic/reducers content (TPC) and radical scavenging ability in parallel expressed significant prevalence of "leaves with flowers" extract vs. "fruits" one. Membrane concentration was shown an effective means for direct increase of bioactive components. A strong correlation between antiradical capacities of the extracts and their TPC was established.

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